GeneticPeace
Transferring Medical Wisdom for the Future of Human Genetics
How does all this matter to the public?

Here are some of the serious risks associated with the perpetuation of the erroneous depiction and understanding of
the female anatomy and the continued use of currently approved (FDA and other agencies around the  
world) catheters for ART.

1. Devices Don’t Match a Woman’s Anatomy: Worldwide, more than 80 million women suffer from infertility are
caught in the financial, emotional and physical vortex associated with traditional Assisted Reproductive Techniques
(ART). The mismatch between reality and practice has caused women to suffer pain, trauma and has damaged the
reproductive systems of millions of individuals. Oftentimes current in vitro fertilization (IVF) techniques are
unsuccessful (25-40% success rates). Hopeful parents often try the procedure multiple times. The  
repeated uterine trauma associated with multiple ART cycles may cause cysts, fibroids, hyperplasia and chronic
menstrual disorders. These complications are seen in 18.2% of patients. Moreover, these complications can further
decrease chances of conception. Other complications associated with ART include: ectopic pregnancy in 1.9%;
abortion in 20.6%; multiple pregnancy in 28%; pregnancy-induced hypertension in 10%; pre-term labor in 21.5%; low
birth weight in 30.5%; and intrauterine death in 2%.

2. Devices are Counter-Productive and Create New Problems: Because of the incongruence between the
anatomy and design, these devices are not only counterproductive, but often add  
to the suffering of hopeful mothers-to-be.

3. Genetic Damage is Permanent and Inheritable: Clinical studies suggest ART increases the risk of birth defects
by 30-40% (Hansen et al. 2005). ART increases risks of congenital malformations and major birth defects and genetic
and imprinting disorders. Common abnormalities are perinatal morbidities, birth defects, developmental disabilities and
retinoblastoma. In some cases these procedures have also been tied to childhood cancer,  
chronic conditions, learning and behavioral disorders and reproductive effects (Schieve et al. 2004). These
developmental abnormalities often affect the physical and mental health of the child, the emotional health of women
and, because the damage is genetic, can also affect the child’s offspring and future generations.

4. Daunting Financial Risks: The cost of a single embryo transfer cycle (IVF) in the U.S. can run tens of thousands
of dollars. The average clinical success rate per cycle is 25-40%. Aspiring parents often repeat this expensive cycle
over and over without insight into the root of the failure - the embryo-transfer device.

5. Hormonal complications: In preparation for the ART procedure, all women are given hormones. Due to the faulty
techniques and devices used currently, many IVF procedures turn out to be unsuccessful. This leads the hopeful
women to repeat the hormone cycles. Over and above the exorbitant financial cost, these hormones have a
cumulative effect on a woman's endocrinology, including high rates of long-term obesity. Psychological stress
associated with repeated failures to conceive can also lead to depression and suicidal tendencies.

6. Ectopic pregnancy and early-pregnancy loss: Linear gynecological instruments that do not conform to the
shape of the uterine passage create a hostile micro-environment for fetus development. Trauma  
associated with traditional ART insertion increases vulnerability to abnormal implantation leading to life-threatening
abnormal pregnancies (such as ectopic pregnancy and placenta previa).
Why the trauma afflicted to the uterus due to error in medical teaching and
practice can cause serious diseases

Background Research

From the very beginning, the nutritional environment is setting gene switches for life. Good
bonding and feeding switches gene positively. Poor nourishment to reproductive cells can have
adverse effects on the epigenetic process controlling implantation, placentation, organ
formation and fetal growth.

Handling of reproductive cells sperm/embryo involves the critical mechanism of imprinting the
gene at the molecular level and may act as a potential risk to disease development due to hidden
genetic variations. Precise risks may remain unclear but cannot be ignored. These risks may be
increased due to creation of a hostile environment at the molecular level, associated with
existing sperm (IUI)/embryo (IVF) transfer technique.

These risks are preventable by 1) making sure that the molecular environment in the reproductive
system has NATURAL physiological composition free of known and unknown anti-fertility factors
(essential for nurturing fast-growing cells) and 2) preserving that natural environment during
intervention of sperm/embryo transfer technique. Clinical Studies

Fortunately, the KamaSoft Catheter is clinically proven to eliminate these risks by preserving the
NATURAL environment at a molecular level (proven over 20 years). Solution
GeneticPeace

150 Years of Undisputed Error

2008 is the sesquicentennial anniversary of the publication of the seminal
medical textbook Gray’s Anatomy of the Human Body (1858). The
medical fraternity has since used this book as the universally accepted
textbook on human anatomy.

Even though this book is certainly worthy of the usage and the respect it
commands, it makes an important error in the depiction of the female
anatomy. Gray’s two-dimensional rendering of the female reproductive
system fails to depict the three-dimensional curvature in the alignment of
the uterus, cervix and vagina. As a result of the perpetuation of this error
in medical knowledge (extended over 150 years), federally approved
gynecological devices worldwide do not conform to the curvature of the
cervix.

Even though gynecologists & federal agencies world-over acknowledge the
existence of the gap between reality and practice, little progress has been
made in catheter development. The use of all current catheters produces
tearing and bleeding and can lead to permanent damage to the
reproductive system. These devices are a major contributing factor to
development of diseases for women and their offspring.
References:

Theriogenology. 2000 Jan 15;53(2):649-58
The effects of the early uterine environment on the subsequent development of embryo and fetus.
Barnes FL.
IVF Labs, LLC, Salt Lake City , Utah 84117 , USA . fbarnes999@aol.com

BJOG. 2005 Dec;112(12):1589-94
Assisted reproduction technology and defects of genomic imprinting.
Allen C, Reardon W.
Human Assisted Reproduction Ireland , Rotunda Hospital , Dublin , Ireland .

BMC Med Res Methodol. 2007 Jun 22;7:25.
Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for
disentangling effects.
Thapar A, Harold G, Rice F, Ge X, Boivin J, Hay D, van den Bree M, Lewis A. Department of Psychological Medicine,
School of Medicine , Heath Park , Cardiff University , UK . thapar@cf.ac.uk

Fertil Steril. 1998 Oct;70(4):638-42
Complications of medically assisted conception in 3,500 cycles.
Serour GI, Aboulghar M, Mansour R, Sattar MA, Amin Y, Aboulghar H.
The Egyptian IVF & ET Center , Maadi, Cairo . serour@iec.egnet.net

Nutr Health. 2007;19(1-2):143-61.
Nurturing the brain nutritionally and emotionally from before conception to late adolescence.
House SH.
McCarrison Society. shhouse@ntlworld.com

Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R133-8.
Imprinting and assisted reproductive technology.
Maher ER. Section of Medical and Molecular Genetics, Institute of Biomedical Research, University of Birmingham
School of Medicine , Edgbaston, Birmingham , UK . e.r.maher@bham.ac.uk

Semin Reprod Med. 2005 Aug;23(3):285-95
Assisted reproduction: the epigenetic perspective.
Horsthemke B, Ludwig M.
Institut für Humangenetik, Universitätsklinikum Essen, Essen , Germany . b.horsthemke@uni-essen.de

Semin Reprod Med. 2005 Aug;23(3):285-95
Genomic imprinting and assisted reproductive technology: connections and potential risks.
Thompson JR, Williams CJ. Center for Research on Reproduction and Women's Health and Division of Reproductive
Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Pennsylvania School of
Medicine, Philadelphia, Pennsylvania 19104, USA.

Genetika. 2007 Sep;43(9):1157-71.
[Epigenetic perspectives of safety in assisted reproductive technologies]
[Article in Russian] Lebedev IN, Puzyrev VP.

J Obstet Gynaecol Can. 2006 Mar;28(3):220-50.
Pregnancy outcomes after assisted reproductive technology.
[Article in English, French]
Allen VM, Wilson RD, Cheung A; Genetics Committee of the Society of Obstetricians and Gynaecologists of Canada
(SOGC); Reproductive Endocrinology Infertility Committee of the Society of Obstetricians and Gynaecologists of
Canada (SOGC).
Halifax, NS , Canada.

Endokrynol Pol. 2005 Nov-Dec;56(6):975-9.
[Health of children born after the infertility treatment with Assisted Reproduction Technology][Article in Polish]
Wołczyński S, Zbucka M, Leśniewska M.
Department of Reproduction and Gynecological Endocrinogy, Medical University in Bialystok , Poland .

Harefuah. 2006 Mar;145(3):223-8, 243-4.
[Assisted reproduction technologies and the risk of fetal, chromosomal and genetic malformations][Article in Hebrew]
Imbar T, Tsafrir A, Lev-Sagie A, Hurwitz A, Laufer N, Holzer H.
Department of Obstetrics and Gynecology, Hadassah University Hospital , Mt Scopus, Jerusalem , Israel .
imbar_1@netvision.net.il

Hum Reprod. 2005 Feb;20(2):328-38. Epub 2004 Nov 26. Links
Assisted reproductive technologies and the risk of birth defects--a systematic review.
Hansen M, Bower C, Milne E, de Klerk N, Kurinczuk JJ.
Centre for Child Health Research, The University of Western Australia Telethon Institute for Child Health Research,
West Perth, Western Australia 6872, Australia. michele@ichr.uwa.edu.au

Ther Clin Risk Manag. 2006 Dec;2(4):355-64.
In vitro fertilization (IVF): a review of 3 decades of clinical innovation and technological advancement.
Wang J, Sauer MV.
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics & Gynecology, College of Physicians &
Surgeons, Columbia University New York, NY, USA.  ------2 MILLION CHILDREN BORN

Hum Reprod. 2005 Feb;20(2):328-38. Epub 2004 Nov 26. Links
Assisted reproductive technologies and the risk of birth defects--a systematic review.
Hansen M, Bower C, Milne E, de Klerk N, Kurinczuk JJ.
Centre for Child Health Research, The University of Western Australia Telethon Institute for Child Health Research,
West Perth, Western Australia 6872, Australia. michele@ichr.uwa.edu.au 30-40%
Accreditation Links: U.S. Patent * French Embassy